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sialic acid
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Sialic acids are a diverse family of sugar units with a nine-carbon backbone and are usually found attached to the outer parts of glycan chains found on the surface of all cell types. They possess many structural and modulatory roles due to their negative charge and hydrophobicity.
References
Schauer R. (2000). Achievements and challenges of sialic acid research. Glycoconjugate journal, 17(7-9), 485–499. Click here to redirect detail information.
Angata, T., & Varki, A. (2002). Chemical diversity in the sialic acids and related alpha-keto acids: an evolutionary perspective. Chemical reviews, 102(2), 439–469. Click here to redirect detail information.
Varki A. (2008). Sialic acids in human health and disease. Trends in molecular medicine, 14(8), 351–360. Click here to redirect detail information.
CAZyme Gene Cluster:
| Substrate | Genome_ID | CGC_ID | CGC_Content | Species Name |
|---|---|---|---|---|
| sialic acid | MGYG000002396 | MGYG000002396_1|CGC6 |
GH33|CBM32,GH33|CBM32,null,9.B.27.2.3
|
Bifidobacterium bifidum |
| sialic acid | MGYG000003370 | MGYG000003370_3|CGC1 |
GH33|CBM40,3.A.1.1.41,3.A.1.1.25,SBP_bac_1,null,GH33|CBM40,CE7
|
Streptococcus mitis_AC |